Xi'an's Og

“The default parameter of KaKs_Calculator was set to estimate the K_a/K_s values, which means that the K_a/K_s value was the average of the output from 15 available algorithms comprising 7 original approximate methods and one maximum likelihood method.”

In their analysis of the philogenic evolution of the potato species, the Nature authors resort to a multiple analysis (à la EJ!) in the above sense, by averaging several results. I remain puzzled by the approach that treats all methods on an equal basis, without trying to ascertain precision and bias by X validation or other tools. (Approximate Bayesian Computing was not used as one of the methods.)

This entry was posted on July 8, 2022 at 12:22 am and is filed under Books, pictures, Statistics with tags ABC, Approximate Bayesian computation, maximum likelihood estimation, multiple analysis, Nature, philogenic trees, potatoes. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.