Archive for tolerance

Jorge’s questionable lecture on secularism [reposted]

Posted in Kids, pictures, Travel with tags , , , , , , , , , , , on January 10, 2025 by xi'an

ABC on brain networks

Posted in Books, pictures, Statistics, University life with tags , , , , , , , , , , , , , on April 16, 2021 by xi'an

Research Gate sent me an automated email pointing out a recent paper citing some of our ABC papers. The paper is written by Timothy West et al., neuroscientists in the UK, comparing models of Parkinsonian circuit dynamics. Using SMC-ABC. One novelty is the update of the tolerance by a fixed difference, unless the acceptance rate is too low, in which case the tolerance is reinitialised to a starting value.

“(…) the proposal density P(θ|D⁰) is formed from the accepted parameters sets. We use a density approximation to the marginals and a copula for the joint (…) [i.e.] a nonparametric estimation of the marginal densities overeach parameter [and] the t-copula(…) Data are transformed to the copula scale (unit-square) using the kernel density estimator of the cumulative distribution function of each parameter and then transformed to the joint space with the t-copula.”

The construct of the proposal is quite involved, as described in the above quote. The model choice approach is standard (à la Grelaud et al.) but uses the median distance as a tolerance.

“(…) test whether the ABC estimator will: a) yield parameter estimates that are unique to the data from which they have been optimized; and b) yield consistent estimation of parameters across multiple instances (…) test the face validity of the model comparison framework (…) [and] demonstrate the scalability of the optimization and model comparison framework.”

The paper runs a fairly extensive test of the above features, concluding that “the ABC optimized posteriors are consistent across multiple initializations and that the output is determined by differences in the underlying model generating the given data.” Concerning model comparison, the authors mix the ABC Bayes factor with a post-hoc analysis of divergence to discriminate against overfitting. And mention the potential impact of the summary statistics in the conclusion section, albeit briefly, and the remark that the statistics were “sufficient to recover known parameters” is not supporting their use for model comparison. The additional criticism of sampling strategies for approximating Bayes factors is somewhat irrelevant, the main issue with ABC model choice being a change of magnitude in the evidence.

“ABC has established itself as a key tool for parameter estimation in systems biology (…) but is yet to see wide adoption in systems neuroscience. It is known that ABC will not perform well under certain conditions (Sunnåker et al., 2013). Specifically, it has been shown that the
simplest form of ABC algorithm based upon an rejection-sampling approach is inefficient in the case where the prior densities lie far from the true posterior (…) This motivates the use of neurobiologically grounded models over phenomenological models where often the ranges of potential parameter values are unknown.”

ABC with inflated tolerance

Posted in Mountains, pictures, Statistics, Travel, University life with tags , , , , , , , , on December 8, 2020 by xi'an

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For the last One World ABC seminar of the year 2020, this coming Thursday, Matti Vihola is speaking from Finland on his recent Biometrika paper “On the use of ABC-MCMC with inflated tolerance and post-correction”. To attend the talk, all is required is a registration on the seminar webpage.

The Markov chain Monte Carlo (MCMC) implementation of ABC is often sensitive to the tolerance parameter: low tolerance leads to poor mixing and large tolerance entails excess bias. We propose an approach that involves using a relatively large tolerance for the MCMC sampler to ensure sufficient mixing, and post-processing of the output which leads to estimators for a range of finer tolerances. We introduce an approximate confidence interval for the related post-corrected estimators and propose an adaptive ABC-MCMC algorithm, which finds a balanced tolerance level automatically based on acceptance rate optimization. Our experiments suggest that post-processing-based estimators can perform better than direct MCMC targeting a fine tolerance, that our confidence intervals are reliable, and that our adaptive algorithm can lead to reliable inference with little user specification.

adaptive ABC tolerance

Posted in Books, Statistics, University life with tags , , , , , , , , , on June 2, 2020 by xi'an

“There are three common approaches for selecting the tolerance sequence (…) [they] can lead to inefficient sampling”

Umberto Simola, Jessi Cisewski-Kehe, Michael Gutmann and Jukka Corander recently arXived a paper entitled Adaptive Approximate Bayesian Computation Tolerance Selection. I appreciate that they start from our ABC-PMC paper, i.e., Beaumont et al. (2009) [although the representation that the ABC tolerances are fixed in advance is somewhat incorrect in that we used in our codes quantiles of the distances to set our tolerances.] This is also the approach advocated for the initialisation step by the current paper.  Although remaining a wee bit vague. Subsequent steps are based on the proximity between the resulting approximations to the ABC posteriors, more exactly with a quantile derived from the maximum of the ratio between two estimated successive ABC posteriors. Mimicking the Accept-Reject step if always one step too late.  The iteration stops when the ratio is almost one, possibly missing the target due to Monte Carlo variability. (Recall that the “optimal” tolerance is not zero for a finite sample size.)

“…the decrease in the acceptance rate is mitigated by the improvement in the proposed particles.”

A problem is that it depends on the form of the approximation and requires non-parametric hence imprecise steps. Maybe variational encoders could help. Interesting approach by Sugiyama et al. (2012), of which I knew nothing, the core idea being that the ratio of two densities is also the solution to minimising a distance between the numerator density and a variable function times the bottom density. However since only the maximum of the ratio is needed, a more focused approach could be devised. Rather than first approximating the ratio and second maximising the estimated ratio. Maybe the solution of Goffinet et al. (1992) on estimating an accept-reject constant could work.

A further comment is that the estimated density is not properly normalised, which lessens the Accept-Reject analogy since the optimum may well stand above one. And thus stop “too soon”. (Incidentally, the paper contains the mixture example of Sisson et al. (2007), for which our own graphs were strongly criticised during our Biometrika submission!)

ABC with Gibbs steps

Posted in Statistics with tags , , , , , , , , , , , , , , , , , on June 3, 2019 by xi'an

With Grégoire Clarté, Robin Ryder and Julien Stoehr, all from Paris-Dauphine, we have just arXived a paper on the specifics of ABC-Gibbs, which is a version of ABC where the generic ABC accept-reject step is replaced by a sequence of n conditional ABC accept-reject steps, each aiming at an ABC version of a conditional distribution extracted from the joint and intractable target. Hence an ABC version of the standard Gibbs sampler. What makes it so special is that each conditional can (and should) be conditioning on a different statistic in order to decrease the dimension of this statistic, ideally down to the dimension of the corresponding component of the parameter. This successfully bypasses the curse of dimensionality but immediately meets with two difficulties. The first one is that the resulting sequence of conditionals is not coherent, since it is not a Gibbs sampler on the ABC target. The conditionals are thus incompatible and therefore convergence of the associated Markov chain becomes an issue. We produce sufficient conditions for the Gibbs sampler to converge to a stationary distribution using incompatible conditionals. The second problem is then that, provided it exists, the limiting and also intractable distribution does not enjoy a Bayesian interpretation, hence may fail to be justified from an inferential viewpoint. We however succeed in producing a version of ABC-Gibbs in a hierarchical model where the limiting distribution can be explicited and even better can be weighted towards recovering the original target. (At least with limiting zero tolerance.)